Health officials in Alberta are on the alert after five people there were recently diagnosed with measles. That follows an ongoing outbreak of the disease in B.C. that, as of May 17, had infected 87 people. Another probable case has been caught in Ontario.
Why is measles continuing to reappear in Canada?
Not that long ago, measles was commonplace. That was before 1970, when routine childhood vaccination programs were implemented. In fact, those who were born here in Canada before 1970 were immunized by naturally acquired infection.
But naturally acquired infections can be dangerous. Measles can cause anything from mild illness with a rash, to serious disease that may feature pneumonia (up to 6% of cases), a need for hospital admission (1%), swelling of the brain (0.1%) or death, especially in children (0.03%).
Given the global burden and impact of measles, a UN Millenium Development Goal was to reduce the number of children who continue to be killed by this disease in developing countries. Ultimately, the goal was only partly reached (annual deaths reduced from 733,000 in 2000 to 164,000 in 2008), mainly because of inability to vaccinate approximately 90% of the population in these resource-poor settings.
Therefore, while effective measles vaccination programs have nearly eliminated the disease from developed countries, measles is repeatedly introduced to Canada from the developing world, where it remains commonplace.
Indeed, the origins of many recent Canadian measles clusters can be traced to a visitor who unwittingly brought the disease here (as occurred in B.C. during the Winter Olympics while we were distracted by the medal haul.)
Ultimately, vaccinating 80 - 90% of the population is the cornerstone of measles containment and elimination. That was achieved in Canada from the 1980s onward. The paradox is that we still see localized outbreaks of measles in Canada in the wake of cases introduced from abroad. Here are a few explanations:
a) Some Canadians continue to refuse the measles vaccine. The now debunked link between measles vaccination and autism has led to low vaccination rates in some communities in developed countries, especially the U.K.
b) Those of us who were children in Canada during the 1970s received only one dose of the measles vaccine. Many new Canadians may have not been vaccinated at all. Beginning in 1996/1997, two doses of vaccine were routinely administered in childhood (at 12 months and again at ages 4 - 6) to provide longer lasting protection.
c) Once a disease is almost eliminated from a community, the protection offered by vaccination may wane after 10 to 15 years. This is why a small percentage of cases are seen in Canadians who have been vaccinated with one or even two doses of vaccination. These vaccinated patients typically get milder illness that those who have never been vaccinated.
Even though measles largely originates in the developing world, screening travelers is not the magic bullet that will keep Canada free of measles. This is because the majority of those who are contagious will not be "picked out" by a screening questionnaire or temperature scanning using costly thermal scanners. Moreover, contagiousness begins up to four days before any symptoms or signs develop.
Measles is highly contagious, being spread to those sharing the same airspace. And when you consider that it takes anywhere from 9 to 21 days from exposure to the development of illness, it becomes evident that screening visitors and returning travellers from developing countries is a futile effort.
Putting this all together, expect to see more news stories on localized measles outbreaks until global reduction -- and perhaps eradication -- of measles can be achieved through UN and WHO efforts.
In the meantime, Canadians have a great vaccine at their disposal.